Maturity-Onset Diabetes Mellitus, also known as Type 2 Diabetes, is a chronic metabolic disorder characterized by high blood sugar levels due to the bodys resistance to the effects of insulin, inability to produce enough insulin, or both. It typically develops in adults over the age of 40 but can also occur in younger individuals, especially in the context of obesity or a strong family history of diabetes. The disease is often related to factors such as physical inactivity, obesity, and poor diet. Symptoms may include increased thirst, frequent urination, unexplained weight loss, fatigue, and blurred vision. If left untreated, it can lead to complications like heart disease, kidney failure, and blindness.
Nephrogenic diabetes insipidus
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In nephrogenic diabetes insipidus, the kidneys produce a large volume of dilute urine because the kidney tubules fail to respond to vasopressin (antidiuretic hormone) and are unable to reabsorb filtered water back into the body.
Often nephrogenic diabetes insipidus is hereditary, but it can be caused by drugs or disorders that affect the kidneys.
Symptoms include excessive thirst and excretion of large amounts of urine.
Diagnosis of nephrogenic diabetes insipidus is based on tests of blood and urine.
Drinking increased amounts of water helps prevent dehydration.
To treat nephrogenic diabetes insipidus, people restrict salt in their diet and sometimes take drugs to reduce the amount of urine excreted.(See also Introduction to Disorders of Kidney Tubules.)
Both diabetes insipidus and the better-known type of diabetes, diabetes mellitus, result in the excretion of large volumes of urine. Otherwise, the two types of diabetes are very different.
Two types of diabetes insipidus exist:In nephrogenic diabetes insipidus, the kidneys do not respond to vasopressin (antidiuretic hormone), so they continue to excrete a large amount of dilute urine.
In central diabetes insipidus, which is more common, the pituitary gland fails to secrete vasopressin .
Nephrogenic diabetes insipidus meaning & definition 1 of Nephrogenic diabetes insipidus.