Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Sugarcoat
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to accentuate or embellish the positive; [selling the benefits]; [upselling]
Sugarcoat meaning & definition 1 of Sugarcoat.
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to address an issue by speaking in a way that appears pleasant and not offensive
Sugarcoat meaning & definition 2 of Sugarcoat.
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a nice way of saying mean things....
Sugarcoat meaning & definition 3 of Sugarcoat.
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Obscuring a known reality; a succinct aphorism usually only understood by poverty-level wage workers.
Sugarcoat meaning & definition 4 of Sugarcoat.
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Making words in a sentence seem kinder than what they are to avoid hurting someones feelings.
Sugarcoat meaning & definition 5 of Sugarcoat.
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Acting soft, cry baby, mommies boys, un-MAN-ning like. This is only identifing males that are non-homo but act like it
Sugarcoat meaning & definition 6 of Sugarcoat.
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Coat (an item of food) with sugar.
Sugarcoat meaning & definition 7 of Sugarcoat.
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to make something seem more positive or pleasant than it really is:
Sugarcoat meaning & definition 8 of Sugarcoat.
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