Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Anthology
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A collection/package chosen by the editor.
Anthology meaning & definition 1 of Anthology.
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A religion started by the coolest person in the world
Anthology meaning & definition 2 of Anthology.
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Modular POS and inventory control system with inventory analysis, purchase orders, offsite sales, reporting, etc. for booksellers. A software product by Anthology
Anthology meaning & definition 3 of Anthology.
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A published collection of poems or other pieces of writing.
Anthology meaning & definition 4 of Anthology.
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