Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Squitch
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A baby sasquatch
Squitch meaning & definition 1 of Squitch.
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a sexual activity that involves the simultaneous squirting of both female partners due to a sex toy, fingering, or other means of achieving orgasm
Squitch meaning & definition 2 of Squitch.
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A person who is both a squid (like in [Rocket Power]) and a bitch.
Squitch meaning & definition 3 of Squitch.
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When your nickname is squirrel and you bitch alot
Squitch meaning & definition 4 of Squitch.
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Squirrel Bitch; Small rodent with the ability of climbing trees to get nuts and being as cruel and sarcastic as possible.
Squitch meaning & definition 5 of Squitch.
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A wet fart, especially the sneaky kind when you feel you can get away with a normal fart before you go to the toilet.
Squitch meaning & definition 6 of Squitch.
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