• The complement system is an enzyme cascade that helps defend against infection. Many complement proteins occur in serum as inactive enzyme precursors (zymogens); others reside on cell surfaces. (See also Overview of the Immune System.)
    The complement system bridges innate and acquired immunity by

    Augmenting antibody (Ab) responses and immunologic memory
    Lysing foreign cells
    Clearing immune complexes and apoptotic cells

    Complement components have many biologic functions (eg, stimulation of chemotaxis, triggering of mast cell degranulation independent of immunoglobulin E [IgE]).


    Complement system meaning & definition 1 of Complement system.


  • a group of proteins that works with other substances as part of the immune system:

    Complement system meaning & definition 2 of Complement system.

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