Approach to the patient with suspected immunodeficiency


  • Immunodeficiency typically manifests as recurrent infections. However, recurrent infections are more likely to have causes other than immunodeficiency (eg, inadequate treatment, resistant organisms, other disorders that predispose to infection). Both clinical and laboratory findings are needed for diagnosis.
    (See also Overview of Immunodeficiency Disorders.)
    Immunodeficiency can be

    Primary: Genetically determined, typically manifesting during infancy or childhood
    Secondary: Acquired

    There are many causes of secondary immunodeficiency, but most immunodeficiencies result from one or more of the following:

    Systemic disorders (eg, diabetes, undernutrition, HIV infection)
    Immunosuppressive treatments (eg, cytotoxic chemotherapy, bone marrow ablation before transplantation, radiation therapy)
    Prolonged serious illness (particularly in critically ill, older, and/or hospitalized patients)

    Primary immunodeficiencies are classified by the main component of the immune system that is deficient, absent, or defective:

    Humoral immunity
    Cellular immunity
    Combined humoral and cellular immunity
    Phagocytic cells
    Complement proteins


    Approach to the patient with suspected immunodeficiency meaning & definition 1 of Approach to the patient with suspected immunodeficiency.

Similar Words

What is Define Dictionary Meaning?

Define Dictionary Meaning is an easy to use platform where anyone can create and share short informal definition of any word.
Best thing is, its free and you can even contribute without creating an account.



This page shows you usage and meanings of Approach to the patient with suspected immunodeficiency around the world.