Have it off is a colloquial phrase that is often associated with sexual activity or intercourse. It is not typically used in formal conversation due to its casual and informal nature. Please note that it is also a regional idiom, more commonly used in British English.

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have it off
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through and through
Through and through describes a situation where an object, real or imaginary, passes completely through another object, also real or imaginary. The phrase has several common uses:
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hemicrania
a severe recurring vascular headache; occurs more frequently in women than men
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western kingbird
a kingbird seen in western United States; head and back are pale grey and the breast is yellowish and the tail is black
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tenderizer
a substance (as the plant enzyme papain) applied to meat to make it tender