Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Link up
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to get together
Link up meaning & definition 1 of Link up.
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when you want to get together or meet up with someone
Link up meaning & definition 2 of Link up.
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to call someone, let someone know whats going on... Link UP The Celly !
Link up meaning & definition 3 of Link up.
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To meet up and engage in sexual activities.
Link up meaning & definition 4 of Link up.
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the act of connecting two things, organizations, etc., for example so that they can work together:
Link up meaning & definition 5 of Link up.
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