Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Oaty
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Someone who is awkward all the time. You feel like you cant even talk to them because they are always slow and they dont talk to you because they deep down hate life. You sometimes feel like you could have a strong bond with this person if they didnt make you feel like shit with there awkwardness.
Oaty meaning & definition 1 of Oaty.
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