Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Hotcakes
-
The fastest selling product in world history. Often used to exagerrate the sell of a product.
Hotcakes meaning & definition 1 of Hotcakes.
-
Its not an offensive or sexual harassing term used as a nickname
Hotcakes meaning & definition 2 of Hotcakes.
-
A nickname for a hot girl
Hotcakes meaning & definition 3 of Hotcakes.
-
a personal treasure,
2)something that is awesome,
3)a bundle of mickeys 40ozers.Hotcakes meaning & definition 4 of Hotcakes.
Similar Words