Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Strapper
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derived in south philly meaning a loser, corny, camar, someone you are embarrassed for because they are corny to the highest level of corn
Strapper meaning & definition 1 of Strapper.
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Loser, scrub, not cool, busted, dumb ass, u can use it to desribe anyone not up to your standards
Strapper meaning & definition 2 of Strapper.
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A stripper with a strap-on.
Strapper meaning & definition 3 of Strapper.
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- An old timey supposed insult used by the impoverished
Strapper meaning & definition 4 of Strapper.
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a fat line of cocaine
Strapper meaning & definition 5 of Strapper.
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Hotty (male) under the age of 25; short for strapping young lad...Originally coined by vail_chick, as a way to describe her younger friends new boyfriend, later adopted to descibe all young juicy men.
Strapper meaning & definition 6 of Strapper.
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A person who grooms racehorses.
Strapper meaning & definition 7 of Strapper.
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