Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Sea horse
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A fabulous creature, half horse and half fish, represented
in classic mythology as driven by sea dogs or ridden by the Nereids. It
is also depicted in heraldry. See Hippocampus.
Sea horse meaning & definition 1 of Sea horse.
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a type of fish whose head and neck look like those of a horse
Sea horse meaning & definition 2 of Sea horse.
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