Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Dill weed
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A person who generaly is not smart. This person cannot realize the obvious and is oblivious to reality.
Dill weed meaning & definition 1 of Dill weed.
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(1.) Pickle plant.(2.) Word Beavis often uses when talking to someone he dislikes.
Dill weed meaning & definition 2 of Dill weed.
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self-censored version of the word [dildo] or the word [dickweed] for use in polite society.
Dill weed meaning & definition 3 of Dill weed.
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