Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Rave slut
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Preferably any woman who attends a Rave that shows more skin than a stripper and more fucked up on drugs than Kurt Cobain. These girls dance around the stage kissing every guy without a shirt on, and takes one of them home (or to the side of the stage) to suck him, fuck him, or a combination of both. After she is finished with the guy, (or female, or both sexes) the slut dips out only to leave him with a lasting memory of her in the form of herpes, chlamydia, aids, or mono
Rave slut meaning & definition 1 of Rave slut.
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Although it is common to think that only girls qualify for this term, it is in fact very possible for a rave slut to be a man. Many men in who try join the rave scene are only there to prey on young girls messed up on drugs. Often they are rich silver spoon fed imports from far off places, such as Alabama. They will come to places like San Francisco, dye their hair different colors and get piercings to fit in, and then act like they are part of the down to earth hippie culture and can understand their struggles, when they have never had to lift a finger or suffer in their life. Usually continue to party past their prime, and look ten times their age because of all the drugs they take.
Rave slut meaning & definition 2 of Rave slut.