Misfortune

[Sarah]

Bad fortune or luck; calamity; an evil accident; disaster;mishap; mischance.Consider why the change was wrought, You 'll find his misfortune, nothis fault. Addison.

[Sarah]

bad luck or an unlucky condition or event

[Little_Girl]

An unfortunate condition or event.

[Julene]

Irish-English ([Limerick])
Someone who is a loser, [unlucky], socially [clueless]