Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Truthful
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When your being a pussy and telling people the what really happened because your a stupid goodie two-shoe
Truthful meaning & definition 1 of Truthful.
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honest and not containing or telling any lies:
Truthful meaning & definition 2 of Truthful.
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(of a person or statement) telling or expressing the truth; honest.
Truthful meaning & definition 3 of Truthful.
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