• The immune response to foreign antigens consists of

    Humoral mechanisms (eg, antibodies)
    Cellular mechanisms

    (See also Tumor Antigens.)
    Most humoral responses cannot prevent tumor growth. However, effector cells, such as T cells, macrophages, and natural killer cells, have relatively effective tumoricidal abilities. Effector cell activity is induced by cells that present tumor-specific antigens (TSAs) or tumor-associated antigens (TAAs) on their surface (these cells are called antigen-presenting cells) and is supported by cytokines (eg, interleukins, interferons). Despite the activity of effector cells, host immunoreactivity may fail to control tumor occurrence and growth.


    Host response to tumors meaning & definition 1 of Host response to tumors.

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