• Interdigital nerve irritation (neuralgia) or persistent benign enlargement of the perineurium (neuroma) can cause pain, which may be nonspecific, burning, or lancinating, or a foreign body sensation. Diagnosis is usually clinical. Treatment may involve correction of footwear, local injection, or sometimes surgical excision.
    (See also Overview of Foot and Ankle Disorders.)
    Interdigital neuralgia is a common cause of metatarsalgia. The interdigital nerves of the foot travel beneath and between the metatarsals, extending distally to innervate the toes. Neuralgia of the interdigital nerve along its distal innervation near the ball of the foot develops primarily as a result of improper or constrictive footwear or, less commonly, nerve traction resulting from abnormal foot structure (eg, splayfoot deformity). As a result of chronic repetitive trauma, a benign thickening of the nerve develops (Morton neuroma).


    Interdigital neuralgia meaning & definition 1 of Interdigital neuralgia.

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