• Osteonecrosis is a focal infarct of bone that may be caused by specific etiologic factors or may be idiopathic. It can cause pain, limitation of motion, joint collapse, and secondary osteoarthritis. Diagnosis is by x-rays and MRI. In early stages, surgical procedures may slow or prevent progression. In later stages, joint replacement may be required for relief of pain and maintenance of function.

    In the US, osteonecrosis affects about 20,000 new patients annually. The hip (femoral head) is most commonly affected, followed by the knee and shoulder (humeral head). The wrist and ankle are less often involved. It is unusual for osteonecrosis to involve the shoulder or other less commonly affected sites without the hip also being involved. Osteonecrosis of the jaw has been associated rarely with antiresorptive therapy for osteoporosis. Osteonecrosis of the jaw has characteristics that differ from osteonecrosis at other sites.


    Osteonecrosis (on) meaning & definition 1 of Osteonecrosis (on).

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