• Down syndrome is a chromosome disorder caused by an extra chromosome 21 that results in intellectual disability and physical abnormalities.

    • Down syndrome is caused by an extra chromosome 21.
    • Children with Down syndrome have delayed physical and mental development, specific head and facial features, and are often short.
    • Before birth, Down syndrome may be suspected based on ultrasonography or tests on the mother

    Down syndrome (trisomy 21) meaning & definition 1 of Down syndrome (trisomy 21).

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