Multiple endocrine neoplasia syndromes (men)

[Renato]

Multiple endocrine neoplasia syndromes are rare, inherited disorders in which several endocrine glands develop noncancerous (benign) or cancerous (malignant) tumors or grow excessively without forming tumors.

Multiple endocrine neoplasia syndromes are caused by gene mutations, so they tend to run in families.
Symptoms vary depending on which glands are affected.
Genetic screening tests can be done to detect disease in family members of people who have multiple endocrine neoplasia syndromes.
No cure is available, but doctors treat the changes in each gland as they occur with surgery or with drugs to control excess hormone production.

Multiple endocrine neoplasia syndromes can appear in infants or in people as old as age 70. These syndromes are usually inherited.
The tumors and the abnormally large glands often produce excess hormones. Although tumors or abnormal growth may occur in more than one gland at the same time, changes often take place over time.
Multiple endocrine neoplasia syndromes are caused by inherited genetic mutations. A single gene responsible for type 1 disease has been identified. Abnormalities in a different gene have been identified in people with types 2A and 2B disease.