Sulfonamides
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Sulfonamides are a class of antibiotics that are effective against many gram-positive bacteria and gram-negative bacteria. Some sulfonamides are applied directly to the skin (topically) to treat burns and skin, vaginal, and eye infections.
Sulfonamides include the following:Mafenide
Sulfacetamide
Sulfadiazine
Sulfadoxine
Sulfamethizole
Sulfamethoxazole (in combination with trimethoprim)
Sulfanilamide
Sulfasalazine
SulfisoxazoleSulfamethoxazole (SMX) is commonly used in combination with trimethoprim (TMP). The combination is called TMP/SMX.
Sulfonamides work by preventing bacteria from producing a form of folic acid they need to grow and multiply.
(See also Overview of Antibiotics.)
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