Effects of liver disorders on drugs

[Raeanne Dimick]

Liver disorders often change the effect of drugs on the body—for example, by changing

How much of the drug is absorbed from the intestine
How quickly and completely the liver metabolizes a drug—for example, changing the drug into an active form or into an inactive form (a form that has no effect on the body)
How much of the drug is transported throughout the body
How quickly the drug is eliminated from the body
How sensitive the body is to a drug