Cirrhosis

[Sarah]

A disease of the liver in which it usually becomes smaller insize and more dense and fibrous in consistence; hence sometimesapplied to similar changes in other organs, caused by increase in thefibrous framework and decrease in the proper substance of the organ.

[Sarah]

The only disease where you die happy.

[Monty]

Cirrhosis is a late stage of hepatic fibrosis that has resulted in widespread distortion of normal hepatic architecture. Cirrhosis is characterized by regenerative nodules surrounded by dense fibrotic tissue. Symptoms may not develop for years and are often nonspecific (eg, anorexia, fatigue, weight loss). Late manifestations include portal hypertension, ascites, and, when decompensation occurs, liver failure. Diagnosis often requires liver biopsy. Cirrhosis is usually considered irreversible. Treatment is supportive.

Cirrhosis is a leading cause of death worldwide.

[Kit]

A chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue. It is typically a result of alcoholism or hepatitis.