Gender dysphoria
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[Gender dysphoria] often occurs in [transgender] or [genderqueer] people. It makes them feel uncomfortable identifying as the gender they were born with, and feeling uncomfortable with their body. It can often make the people going through this depressed.
Gender dysphoria meaning & definition 1 of Gender dysphoria.
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the unhappy feeling that some people have when they feel that their identity (= who they are) as a man or a woman does not fit with the sex that they had, or were said to have, at birth:
Gender dysphoria meaning & definition 2 of Gender dysphoria.