Kuru

[Becky]

A fatal disease of the brain occurring in some peoples in New Guinea and thought to be caused by a virus-like agent such as a prion.

[Tina]

an engineer, [self proclaimed] as the best; a person who refers to themself in 3rd person; someone who is referred by sexy british women as the sexiest human being ever; one who gets [lotsa] booty; one who is often desired by a [pevil].

[Oralee]

1. An exclamation of excitement

2. [A furry] [elk] looking animal from Africa

3. [Brain disease]

[Justin Bieber]

I [great band] out of [Jersey City]....with the sexiest [drummer] ever

[Julene]

Kuru is a prion disease that now occurs rarely if ever. It causes rapid deterioration of mental function and loss of coordination. This disease was once common among the Fore natives of the Papua New Guinea highlands and was transmitted by cannibalism that was part of the native burial ritual.
(See also Overview of Prion Diseases.)
Scientists have been interested in kuru mainly because it shows how prion diseases can be transmitted from person to person.
Until the early 1960s, kuru was fairly common in Papua New Guinea. Prions were probably acquired during a burial ritual, which involved eating tissues of a dead relative as a sign of respect (called ritual cannibalism). Kuru probably started when prion-contaminated tissues from a person with Creutzfeldt-Jakob disease were eaten. Kuru was more common among women and children because they were given the brains, which were more infectious. These rituals have been prohibited since the 1950s, and kuru has been virtually eliminated. Few, if any, people develop kuru anymore. However, 11 cases of kuru were reported between 1996 and 2004. These cases suggest that after a person is infected, symptoms may not develop until more than 50 years later.
The first symptoms of kuru include loss of coordination (ataxia), difficulty walking, and shaking (tremors) that resembles shivering (kuru means to shake).
Later, abnormal involuntary movements, such as repetitive, slow writhing or rapid jerking of the limbs and body (called choreoathetosis), may develop. The limbs become stiff, and muscles jerk (called myoclonus). Emotions may switch suddenly from sadness to happiness with sudden outbursts of laughter. People with kuru become demented and eventually placid, unable to speak, and unresponsive to their surroundings.
Most people with kuru die within 24 months after symptoms appear, usually as a result of pneumonia or infection due to bedsores (pressure sores).
No effective treatment is available. Treatment of kuru focuses on relieving symptoms.

[Lanell]

Kuru is a rare prion brain disease endemic to Papua, New Guinea, and thought to be spread by ritual cannibalism.
(See also Overview of Prion Diseases.)
Although ritual cannibalism ended in the 1950s, 11 new cases of kuru have been reported between 1996 and 2004, suggesting an incubation period that may exceed 50 years.
Symptoms of kuru begin with tremors (resembling shivering) and ataxia. Movement disorders such as choreoathetosis, fasciculations, and myoclonus develop later, followed by dementia.
Cerebrospinal fluid (CSF) testing does not appear to be useful. Few other test results have been reported. No diagnostic abnormalities have been identified in the PrP gene of people with kuru. However, a PrP gene variation that protects against prion disease has been identified in people in the Papua population who have not contracted kuru (1). Autopsy can show typical PrPSc-containing plaques, with the greatest density in the cerebellum.
Death usually occurs within 2 years after symptoms begin; cause of death is usually pneumonia or infection due to pressure sores.
There is only supportive treatment for kuru.