Enervate

[Vania]

Make (someone) feel drained of energy or vitality.

[Laresvog 0]

disturb the composure of

[DebrahCom]

weaken mentally or morally

[Urooj.Zafar]

To reduce strength or energy; debilitate.

[productkeypro]

To weaken morally or mentally.

[Luis Fok]

To unnerve or faze.

[Sommer]

To partially or completely remove a nerve.

[sky]

Made feeble; weakened.

[dipangkarbos]

Muscle fatigue is the decline in ability of muscles to generate force. It can be a result of vigorous exercise but abnormal fatigue may be caused by barriers to or interference with the different stages of muscle contraction. There are two main causes of muscle fatigue: the limitations of a nerve’s ability to generate a sustained signal (neural fatigue); and the reduced ability of the muscle fiber to contract (metabolic fatigue).

[DennisSt]

weakened; weak; without strength of force

[Agnes]

en-ėr′vāt, v.t. to deprive of nerve, strength, or courage: to weaken.—adj. weakened: spiritless.—n. Enervā′tion.—adj. Ener′vative.—v.t. Enerve′ (obs.), to enervate. [L. enervāre, -ātum—e, out of, nervus, a nerve.]

[Dianne]

To weaken; to deprive of force; to emasculate.