Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Defend
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To deny the right of the plaintiff in regard to (the suit, orthe wrong charged); to oppose or resist, as a claim at law; tocontest, as a suit. Burrill.
Defend meaning & definition 1 of Defend.
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In America this means terminating anyone and everyone for their own personal security, even if it meant the entire world would be destroyed. It's also common to attack weak countries that could possibly stand up against them in certain ways, or for national benefit.
And then call it Defending
This can also be described as: Fighting
Defend meaning & definition 2 of Defend.
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