Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Peanut gallery
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[george bush]s presidential cabinet
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a group of (sometimes stupid) people that make comments on something they are watching or listening to; spectators with a verbal opinion
Peanut gallery meaning & definition 1 of Peanut gallery.
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a person group of people whose opinions are insignificant
Peanut gallery meaning & definition 2 of Peanut gallery.
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The term originated back in the theatre, where the cheapest seats were those way at the bottom floor and where people purchased peanuts because they were the cheapest snack. If they disapproved of the performance, they would throw the peanuts.
Howdy Doody, a show that started in the 1940s (not 50s), the children in the crowd were considered the Peanut Gallery.Peanut gallery meaning & definition 3 of Peanut gallery.
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term used on the 50s tv show Howdy Doody for the audience of kids.
Peanut gallery meaning & definition 4 of Peanut gallery.
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Someone who has squirrel brains. Anything they say should and will be ignored.
Peanut gallery meaning & definition 5 of Peanut gallery.
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[george bush]s presidential cabinet
or
a group of (sometimes stupid) people that make comments on something they are watching or listening to; spectators with a verbal opinionPeanut gallery meaning & definition 6 of Peanut gallery.
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likes cock
Peanut gallery meaning & definition 7 of Peanut gallery.