Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Awww
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THe response to a compliment; to express the appreciation of
Awww meaning & definition 1 of Awww.
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Used to express a sentimental reaction to [warm fuzzy] experiences. (The number of Ws at the end is arbitrary, but at least two or three normally occur in this word.)
Awww meaning & definition 2 of Awww.
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Something used when someone pays you a compliment, or if youre told something cute/sweet.
Awww meaning & definition 3 of Awww.
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A common exclamation used to express:
1.)Adoration
2.) Lethargy
3.) Dismay
4.) PityMostly used by women, but not always.
Awww meaning & definition 4 of Awww.
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An expression of dissapointment.
Awww meaning & definition 5 of Awww.
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The words that mean you just entered the friend zone.
Awww meaning & definition 6 of Awww.
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To feel sorry for someone
Awww meaning & definition 7 of Awww.
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The verbal equivalent of receiving a [bitchslap] to the groin. The male version of a [cunt-punt]. If said to a female while being a male, you are [automagically] their bitch or gay friend. See [Ken doll] . If said to a female while being a female, they will squee in response like a stuck pig.
Awww meaning & definition 8 of Awww.