Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Reggie
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regular weed
Reggie meaning & definition 1 of Reggie.
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A sexy,fine,tall,dark chocolate dude who has a long dick.
Reggie meaning & definition 2 of Reggie.
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A big ass white dog
Reggie meaning & definition 3 of Reggie.
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when something is dank, ratchet and/or disgusting
Reggie meaning & definition 4 of Reggie.
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Really ignorant and obnoxious person, often a regular drug dealer
Reggie meaning & definition 5 of Reggie.
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A black kid who is really obnoxious. Bestfriends are 8th grade girls and he is 18. Sucks at football!
Reggie meaning & definition 6 of Reggie.
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Registered sex offender; someone who is creepy.
Reggie meaning & definition 7 of Reggie.
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Reggie- a poker player that has no idea how to fucking play, a complete moron
Reggie meaning & definition 8 of Reggie.
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left [earbud] used to mildly cut awkward [cacophony] when well- hung [tenant] is fucking the life out of an unexpected house guest whom he failed to request landlordian permission to issue an overnight invitation
Reggie meaning & definition 9 of Reggie.
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a large curved erect penis.
Reggie meaning & definition 10 of Reggie.
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left [earbud] used to mildly cut awkward [cacophony] when well- hung [tenant] is fucking the life out of an unexpected house guest whom he failed to request landlordian permission to issue an overnight invitation
Reggie meaning & definition 11 of Reggie.