D.u.f.f.
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An abbreviation for Designated Ugly Fat Friend. Often in many large groups of women (usually adolecents) there will be a D.U.F.F. as a means to look better by comparison.
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The Designated (/Dumb) Ugly Fat Friend.
The cock-blocking friend of the hot chick youre trying to hook up with, often the target of the wingman.
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