Sedation

[Sarah]

1. a state of calm or reduced nervous activity; [chilled] out
2. [date rape] drug (also called a [mickey])

[Zipporah Schumaker]

the use of a drug or other means to make someone calm or to make them go to sleep:

[Couch Potatoe]

The administering of a sedative drug to produce a state of calm or sleep.