Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Fatalist
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One who maintains that all things happen by inevitablenecessity.
Fatalist meaning & definition 1 of Fatalist.
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a team in counter-strike that had a team member named chobo which thnks he is really good but he actually a newb in korean language and i i am willing to bet that chobo is actually korean.
- Fatalist lost to #team.umz in finals
Fatalist meaning & definition 2 of Fatalist.
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One who practices the arts of being fatal at all times. A person who is always looking to argue or bring fourth actions that may and probably will cause one to be fatal.
Fatalist meaning & definition 3 of Fatalist.
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