Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Typhoon
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A violent whirlwind; specifically, a violent whirlwindoccurring in the Chinese seas.
Typhoon meaning & definition 1 of Typhoon.
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The act of receiving fellatio, and causing the giver to laugh right as one orgasms, making semen come out the giver's nose.
Typhoon meaning & definition 2 of Typhoon.
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a large whirlwind, hurricane, et cetera
Typhoon meaning & definition 3 of Typhoon.
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A man puts on three strapons, one facing behind, one facing left and one facing right, then gets 4 women and has sexual relations with them all at the same time by doing a circular motion with his hips.
Typhoon meaning & definition 4 of Typhoon.
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Fastest production SUV ever!
Typhoon meaning & definition 5 of Typhoon.
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An internet troll called Liam.
The hacker on steroids.
A member with 'Legendary' status on Voide.org
The idiot who spread the Cutenews 4.0.1 exploit.Typhoon meaning & definition 6 of Typhoon.
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Filling up a large garbage bin/can and leaning it up against someone's door so when the door opens inward, the water flows out all over the persons room and stuff
Typhoon meaning & definition 7 of Typhoon.
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A type of hairstyle sported by Prince in the early 90s. Very puffy on top.
Typhoon meaning & definition 8 of Typhoon.
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a big boss in a district
Typhoon meaning & definition 9 of Typhoon.
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When a woman spits on your testicles, then blows on them, all while she jerks you off.
Typhoon meaning & definition 10 of Typhoon.
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Slang for an African-American.
See [Nigger].
Typhoon meaning & definition 11 of Typhoon.
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A tropical storm in the region of the Indian or western Pacific oceans.
Typhoon meaning & definition 12 of Typhoon.