Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Muller
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A stone or thick lump of glass, or kind of pestle, flat at thebottom, used for grinding pigments or drugs, etc., upon a slab ofsimilar material.
Muller meaning & definition 1 of Muller.
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a chill ass bro who plays 7 hours of tennis a day macks on every piece of ass he sees and says incredibly racist comments whenever he feels like it
Muller meaning & definition 2 of Muller.
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To intentionally injure an opponent in rugby by smashing them in a tackle.
Muller meaning & definition 3 of Muller.
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To make a joke that fails and everyone laughs at you and not with you.
Can also be judged by a thumbs up or thumbs down.Muller meaning & definition 4 of Muller.
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when you stick your finger up someones anus
Muller meaning & definition 5 of Muller.
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has an extreamily small dick and is veary lazy
Muller meaning & definition 6 of Muller.
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To do a shit (eject shit from uranus)
Used as verbal abuse (youMuller meaning & definition 7 of Muller.
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A last name usually paired with a first name of someone who is attractive. Normally an 'Alisha' or 'Jake'
Muller meaning & definition 8 of Muller.
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Usually a word meant to imply high levels of intoxication, muller, when applied to one who is of or nearly of a personal substance-free attitude, can be also construed to mean one
Muller meaning & definition 9 of Muller.
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Being calmly intoxicated to a near paralytic level. Generally through the aid of alcohol.
Muller meaning & definition 10 of Muller.
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To take something that belongs to someone else, even though it can clearly be traced back to you.
Muller meaning & definition 11 of Muller.