diazoxide

[DavfidasrJonia]

vasodilator (trade name Hyperstat) used to treat severe hypertension

[Vania]

A potassium channel activator which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions, used as a vasodilator to treat hypertension and in diabetes to decrease the secretion of insulin.

[KalanNug]

Diazoxide, sold under the brand name Proglycem and others, is a medication used to treat low blood sugar due to a number of specific causes. This includes islet cell tumors that cannot be removed and leucine sensitivity. It can also be used in refractory cases of sulfonylurea toxicity. It is generally taken by mouth.Common side effects include high blood sugar, fluid retention, low blood platelets, a fast heart rate, increased hair growth, and nausea. Other severe side effects include pulmonary hypertension and heart failure. It is chemically similar to thiazide diuretics. It works by decreasing insulin release from the pancreas and increasing glucose release by the liver.Diazoxide was approved for medical use in the United States in 1973. It is on the World Health Organizations List of Essential Medicines. It is available as a generic medication.

[mehmood]

A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.