Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Prototype
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An original or model after which anything is copied; thepattern of anything to be engraved, or otherwise copied, cast, or thelike; a primary form; exemplar; archetype.They will turn their backs on it, like their great precursor andprototype. Burke.
Prototype meaning & definition 1 of Prototype.
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a girl who stands a more than good chance of being the
Prototype meaning & definition 2 of Prototype.
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Upcoming game for Xbox 360, PS3 and PC. Release for June-July '09.
You play as a shape-shifter with no knowledge of your past and must fight your way through New York City to recover your previous life.
The game is open-worlded, like GTA IV, Assasin's Creed and Halo 3: ODST all roled into one.Prototype meaning & definition 3 of Prototype.
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a sample of a much better design
Prototype meaning & definition 4 of Prototype.
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Something which [at its] current stage has been [screwed up] by [developers] and cannot yet be used by the general public
Prototype meaning & definition 5 of Prototype.
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Arguably the most under-rated metal band out there. They gained popularity with [the songs] appearance of The Way it Ends in [Guitar Hero 3]. A [great band] with a promising future.
Prototype meaning & definition 6 of Prototype.
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1.) someone who is a pimp, [manwhore], or [ladies man]
2.) coolest person at the party
3.) cool, [flashy], extreme, awesome
4.) person you saw on findapix
5.) someone who is very elite at counter-strikePrototype meaning & definition 7 of Prototype.
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A first or preliminary version of a device or vehicle from which other forms are developed.
Prototype meaning & definition 8 of Prototype.