Acquired platelet dysfunction

[Julian]

Acquired platelet dysfunction, which is common, may result from aspirin , other nonsteroidal anti-inflammatory drugs (NSAIDs), or systemic disorders.
(See also Overview of Platelet Disorders.)
Acquired abnormalities of platelet function are very common. Causes include

Drugs
Systemic disorders
Cardiopulmonary bypass

Acquired platelet dysfunction is suspected and diagnosed when unusual or prolonged bleeding is observed and other possible diagnoses (eg, thrombocytopenia, coagulation abnormalities) have been eliminated. Platelet aggregation studies are unnecessary.