Nettlesome
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Topic or subject which is not easy to discuss/understand. It may also be used [in case of] an issue from which it is very difficult to draw [valid] conclusions from, due to its [complexity] or the lack of expertise on the subject from the speaker, for example.
Nettlesome meaning & definition 1 of Nettlesome.
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Causing annoyance or difficulty.
Nettlesome meaning & definition 2 of Nettlesome.