Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Wrinkly
-
Full of wrinkles; having a tendency to be wrinkled; corrugated;puckered. G. Eliot.His old wrinkly face grew quite blown out at last. Carlyle.
Wrinkly meaning & definition 1 of Wrinkly.
-
A cute old person
Wrinkly meaning & definition 2 of Wrinkly.
-
An elderly person.
An old [croc] face.
An old fart.
An old [aged] [pensioner].Wrinkly meaning & definition 3 of Wrinkly.
-
Clothes sitting in [the laundry] [basket] not getting [folded]...
Wrinkly meaning & definition 4 of Wrinkly.
-
Having many lines or folds.
Wrinkly meaning & definition 5 of Wrinkly.
Similar Words