Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Regulator
-
Someone who solve problems using necessary violence, wich is of course necessary in a lot of cases.
Regulator meaning & definition 1 of Regulator.
-
see [Nate Dogg] or [Warren G].
Regulator meaning & definition 2 of Regulator.
-
A very violent and brutal gang started in 1998, the gang mostly frequents Minnesota but is spreading throught the midwest
Regulator meaning & definition 3 of Regulator.
-
n. A motorist who drives the speed limit or slower, no matter how long the line of traffic following is. This usually leads to suggestions being made by those in line as to what said motorist should be doing instead. Aggressive driving and road rage incidents occasionally accompany the experience of being regulated (vb.).
Regulator meaning & definition 4 of Regulator.
-
Keeping things real;
Brittany and Yoli:regulating things
keeping it real
On the down lowRegulator meaning & definition 5 of Regulator.
-
People who Bring authority to a chaotic situation.
Regulator meaning & definition 6 of Regulator.
-
A person or thing that regulates something.
Regulator meaning & definition 7 of Regulator.