Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Gossamer
-
A big red fuck
That gigantic red hairy monster that often chased bugs bunny.
A cobweb on a bush
Gossamer meaning & definition 1 of Gossamer.
-
A fine, filmy substance consisting of cobwebs spun by small spiders, seen especially in autumn.
Gossamer meaning & definition 2 of Gossamer.
-
When you [spew] something completely random, non-sequitor, or [out of context] in the middle of a conversation.
see also: [gossamerfawn]
Gossamer meaning & definition 3 of Gossamer.
-
Traditionally meaning a fine, [filmy] substance consisting of [cobwebs] spun by small spiders, which is seen especially in autumn. Though it is used by a select few as an [alternate term] for goddamnit, following an autocorrect fail.
Gossamer meaning & definition 4 of Gossamer.
-
A word used by intelligent people to describe under water [farts]. Usually in [baths] or hot [tubs].
Gossamer meaning & definition 5 of Gossamer.
-
A very [weak], easyly [pushed] around person who [cant] think for him/her self.
Gossamer meaning & definition 6 of Gossamer.
-
Soneone who can touch you, [feel you up], or steal [stuff thats] in your hands wuthout you noticing or feeling them. Usually thieves or perverts, however sometimes there skills [come in handy].
Gossamer meaning & definition 7 of Gossamer.
-
the very thin thread that spiders produce to make webs
Gossamer meaning & definition 8 of Gossamer.