Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Naught
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Early English term, it basically is another way to say the word nothing.
Naught meaning & definition 1 of Naught.
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A symbol 0 that represents nothing. (A symbol representing nothing however is surely something
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A symbol used in the [1337] or [eleet] alphabet to replace o or O for no paticular reason whatsoever. Makes them believe they have some devine power over people who speak english, or other understandable langauges.
Naught meaning & definition 2 of Naught.
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Absolutely not. A way of completely rejecting something that someone has said. (The word for 0)
Naught meaning & definition 3 of Naught.
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Naught: referring to the sphincta of ones anus.
Derived from the fact that the sphincta looks similar to that of the number naught (0)Naught meaning & definition 4 of Naught.
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The outcome of a naughty attitude, actions.
Naught meaning & definition 5 of Naught.
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an ulgy girl. derived from scoring girls out of ten.
Naught meaning & definition 6 of Naught.
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bring to naught
Naught meaning & definition 7 of Naught.
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Ruin or foil.
Naught meaning & definition 8 of Naught.
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