Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Frill
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a short way of saying for real.
Frill meaning & definition 1 of Frill.
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Sanitized substitution for the word Fuck on Farscape.
Frill meaning & definition 2 of Frill.
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Frill is a short version of for real.
Frill meaning & definition 3 of Frill.
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shorted form of for real. used in a lot of txt messages and online social websites.
Frill meaning & definition 4 of Frill.
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Frill meaning: Cool, Fresh, Awesome etc
Frill meaning & definition 5 of Frill.
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A strip of gathered or pleated material sewn on to a garment or larger piece of material as a decorative edging or ornament.
Frill meaning & definition 6 of Frill.
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[a little bitch] ass that doesnt [wanna go] [swimming].
Frill meaning & definition 7 of Frill.
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