Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Pritch
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Pritch is a combined word of Princess and Bitch. Use it to describe a some bitch that always acts like a princess and you just couldnt stand it.
Pritch meaning & definition 1 of Pritch.
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A morphed form of [prick] and [bitch]. Proper usage would be in a situation wherein the gender of the insultee cannot be easily determined.
Pritch meaning & definition 2 of Pritch.
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a person that is a prep, and a total bitch
Pritch meaning & definition 3 of Pritch.
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Someone who is a fucking bitch and prima-donna AND princess all rolled into one. May be applied to EVERYBODY. Equal opportunity word. Use it well, use it often because this word describes some of your girlfriends
Pritch meaning & definition 4 of Pritch.
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A cross between a pirate and a witch obviously!
Pritch meaning & definition 5 of Pritch.
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A word to replace fail.
Pritch meaning & definition 6 of Pritch.
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Short for pretty little bitch.
Pritch meaning & definition 7 of Pritch.
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small in size, skinny
Pritch meaning & definition 8 of Pritch.
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A sharp-pointed tool or implement; specifically †(a) English regional (East Anglian) a tool for making stake-holes; (also) an eel-spear (obsolete); (b) English regional (west.) a prop for a cart.Compare
Pritch meaning & definition 9 of Pritch.