Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Flanning
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Making plans that one does not intend to keep. It is flake planning. The purpose of flanning is to make it seem to the other person that you like them and want to spend time with them, when in reality you are hoping they cancel first so you dont have to see them.
When two people flan with each other, it becomes a game of chicken, each one waiting for the other to break and cancel first.
Flanning meaning & definition 1 of Flanning.
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just doing doing nothing, or just hanging out.
Flanning meaning & definition 2 of Flanning.
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To Lick Chocolate Off of Someone
Flanning meaning & definition 3 of Flanning.
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