Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Stookie
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A rigid dressing, usually made of gauze and plaster of Paris, used to immobilize an injured body part, as in a fracture or dislocation. Also called plaster cast.
Stookie meaning & definition 1 of Stookie.
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The word Stookie is used to refer to a Headbutt in Glasgow, Scotland and its satellite towns.
Stookie meaning & definition 2 of Stookie.
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originated from the latin word stükié
adj; stupid,idiot
v; get trashed;intoxicatedStookie meaning & definition 3 of Stookie.
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POOP; a shit; crap; a non wet dookie.
Stookie meaning & definition 4 of Stookie.
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Similar to [word]stook, this is a term for a Honda S2000. While stook is the spoken form of s2k (s too k), stookie is another form.
Stookie meaning & definition 5 of Stookie.
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Mandys dookie that she catches and leaves in the trash can...face up, with peanuts and vegies in it. Looks like splatter painted vegetable soup. Sometimes there may be hay in it too.
Stookie meaning & definition 6 of Stookie.
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The act of getting hammered off of one beer and a shot of rum.
Stookie meaning & definition 7 of Stookie.
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