Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Crepuscular
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Formal:
Refers to an animal that is active during [twilight].
Slang:
Refers to a human that is active at night.
(See also: [Insomnia], [nocturnality]
Crepuscular meaning & definition 1 of Crepuscular.
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of, resembling, or relating to twighlight.
-ZOOLOGY (of an animal) appearing or active in twighlightCrepuscular meaning & definition 2 of Crepuscular.
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its basically just an alternative to [awesome]
Crepuscular meaning & definition 3 of Crepuscular.
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Crepuscular meaning & definition 4 of Crepuscular.
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Resembling or relating to twilight.
Crepuscular meaning & definition 5 of Crepuscular.
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