Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Nutting
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To vandalize a private property by throwing several boxes of donuts and various confections at it; including on the lawn, roof, porch, car, etc. Nuttings popularity stems from how quick it is; over 100 donuts can be discarded in about a minute and a half.
Nutting meaning & definition 1 of Nutting.
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The most filth ridden dorm on all of Vermont Technical College campus. Where intelligence dies, and even the cat has herpes.
Nutting meaning & definition 2 of Nutting.
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Headbutting someone (UK)
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Male ejaculation (US)
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To hit ones nuts/testicles (US)
Nutting meaning & definition 3 of Nutting.
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The act of not wearing underwear.
Nutting meaning & definition 4 of Nutting.
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The art of nutting is a finely crafted art that allowes one to laugh uncontrollably at whatever one pleases. Everyone has their own source for nutting. Find yours.
Nutting meaning & definition 5 of Nutting.
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a bunch of people going crazy over something.
Nutting meaning & definition 6 of Nutting.
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NUTTING \ NUH-ting \ adjective;
The act of passing out whilst trying to formulate a response to basic conversation.
Nutting meaning & definition 7 of Nutting.
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Creatively showing a person or a group of people ones testicles and/or penis.
Nutting meaning & definition 8 of Nutting.
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Large amounts of [mixed nuts] what did you think some type of [inappropriate] [manner]
Nutting meaning & definition 9 of Nutting.
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For a man to Come, [semen] [coming out] of [dick].
Nutting meaning & definition 10 of Nutting.
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present participle of nut
Nutting meaning & definition 11 of Nutting.